Comparison 8. Exploration of heterogeneity: breastfeeding.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Breastfeeding allowed during vaccination	13		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
1.1 Rhesus rotavirus vaccines	4	3652	Risk Ratio (M‐H, Random, 95% CI)	0.52 [0.32, 0.86]
1.2 Bovine rotavirus vaccines	9	3452	Risk Ratio (M‐H, Random, 95% CI)	0.64 [0.48, 0.85]
2 Breastfeeding not allowed for at least one hour before and after vaccination	23		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
2.1 Rhesus rotavirus vaccines	15	8468	Risk Ratio (M‐H, Random, 95% CI)	0.61 [0.51, 0.73]
2.2 Bovine rotavirus vaccines	6	954	Risk Ratio (M‐H, Random, 95% CI)	0.45 [0.21, 0.94]
2.3 Human rotavirus vaccines	2	496	Risk Ratio (M‐H, Random, 95% CI)	0.49 [0.12, 1.99]
3 No information	4		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
3.1 Rhesus rotavirus vaccines	1	1185	Risk Ratio (M‐H, Random, 95% CI)	0.70 [0.56, 0.87]
3.2 Bovine rotavirus vaccines	2	877	Risk Ratio (M‐H, Random, 95% CI)	0.58 [0.20, 1.71]
3.3 Human rotavirus vaccines	1	1986	Risk Ratio (M‐H, Random, 95% CI)	0.35 [0.24, 0.51]