Clark 1995.

Methods	Randomization: no details Allocation concealment: no details Blinding: double (no further details) Data collection: no information Intention to treat: no Interim analysis: none Exclusion from analysis: 12/417 were not evaluated, no further details Follow‐up period: 1 week after each vaccination; 1 rotavirus season after vaccination
Participants	Age: 2 to 6 months Health status: no information Breastfeeding: no information Immunization status: no information
Interventions	1. Human‐bovine QHBRV, 4 x 10^7 PFU, 3 doses (n = 199) 2. Placebo (no details), 3 doses (n = 206)
Outcomes	1. Safety: clinical symptoms within 7 days of each vaccination 2. Efficacy: gastroenteritis within 1 rotavirus season of vaccination
Notes	Study location: USA Clinical symptoms: clinical evaluation; severity score measured by modified Duffy 1986 scale Laboratory studies: stool analysis by solid phase immunoassay and electropherotype analysis