Comparison 1. Phenobarbitone compared to placebo or nothing.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Death within 6 months in all trials	3	573	Risk Ratio (M‐H, Fixed, 95% CI)	1.16 [0.85, 1.58]
2 Death within 6 months in adequately concealed trials only	2	388	Risk Ratio (M‐H, Fixed, 95% CI)	2.0 [1.20, 3.33]
3 Convulsions within 4 weeks	3	573	Risk Ratio (M‐H, Fixed, 95% CI)	0.30 [0.19, 0.45]
4 Physical handicap within 4 weeks	1	340	Risk Ratio (M‐H, Fixed, 95% CI)	0.6 [0.27, 1.33]