MEDLINE (OVID)

EMBASE (OVID)

[1] anticonvulsants/ [2] anticonvulsant$.tw. [3] antiepileptic$.tw. [4] seizures/ [5] seizure$.tw. [6] convulsions/ [7] convulsion$.tw. [8] 1 or 2 or 3 or 4 or 5 or 6 or 7 [9] exp malaria/ [10] malaria, cerebral/ [11] malaria.tw. [12] 9 or 10 or 11 [13] 8 and 12 [14] randomized controlled trials/ [15] randomized‐controlled‐trial.pt. [16] controlled‐clinical‐trial.pt. [17] random allocation/ [18] double‐blind method/ [19] single‐blind method/ [20] 14 or 15 or 16 or 17 or 18 or 19 [21] exp clinical trials/ [22] clinical‐trial.pt. [23] (clin$ adj trial$).ti,ab. [24] ((singl$ or doubl$ or trebl$ or tripl$) adj (blind$ or mask$)).ti,ab. [25] placebos/ [26] placebo$.ti,ab. [27] random$.ti,ab. [28] 21 or 22 or 23 or 24 or 25 or 26 or 27 [29] research design/ [30] comparative study/ [31] exp evaluation studies/ [32] follow‐up studies/ [33] prospective studies/ [34] (control$ or prospective$ or volunteer$).ti,ab. [35] 30 or 31 or 32 or 33 or 34 [36] 20 or 28 or 29 or 35 [37]13 and 36 [38] limit 37 to human

[1] anticonvulsive agent/ [2] anticonvulsant$.tw. [3] antiepileptic.tw. [4] seizure/ [5] "seizure, epilepsy and convulsion"/ [6] convulsion/ [7] seizure$.tw. [8] convulsion$.tw. [9] 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 [10] exp malaria/ [11] brain malaria/ [12] malaria.tw. [13] 10 or 11 or 12 [14] 9 and 13 [15] randomized controlled trial/ [16] controlled study/ [17] case control study/ [18] randomization/ [19] double blind procedure/ [20] single blind procedure/ [21] (control$ adj trial$).ti,ab. [22] 15 or 16 or 17 or 18 or 19 or 20 or 21 [23] exp clinical trials/ [24] exp multicenter study/ [25] (clin$ adj trial$).ti,ab. [26] (clin$ adj stud$).ti,ab. [27] ((singl$ or doubl$ or trebl$ or tripl$) adj (blind$ or mask$)).ti,ab. [28] placebo/ [29] placebo$.ti,ab. [30] random$.ti,ab. [31] 23 or 24 or 25 or 26 or 27 or 28 or 29 or 30 [32] methodology/ [33] comparative study/ [34] evaluation/ [35] follow up/ [36] prospective study/ [37] (control$ or prospectiv$ or volunteer$).ti,ab. [38] 33 or 34 or 35 or 36 or 37 [39] 22 or 31 or 32 or 38 [40]14 and 39 [41] limit 40 to human