Date	Event	Description
3 November 2008	Amended	Converted to new review format with minor editing.
11 January 2005	Amended	Issue 2, 2005 (Deviations from protocol) (1) Title: changed from 'Pre‐packaged drugs for treating malaria' to 'Unit‐dose packaged drugs for treating malaria' for a more specific definition of the intervention. (2) Types of intervention: different drug formulations may now be used in the intervention and control arms, as these may form useful comparisons, but we will not combine the data with data from studies using the same formulation in intervention and control arms. (3) Types of outcomes: treatment failure outcome measures altered to conform to new standards; this involved removing "parasite failure rate" and replacing "early" and "late" treatment failure with treatment failure on or by day 14/28. (4) Methods of the review: inclusion of 80% of all randomized participants considered adequate, rather than 90%, to take into account the difficulty in carrying out studies of this type of intervention.