TABLE E1.
Results of 2 to 5 class models from latent class analysis
| 2-Class model | 3-Class model | 4-Class model | 5-Class model | |
|---|---|---|---|---|
| Model fit statistics | ||||
| Log likelihood | –10,875 | –10,279 | –10,148 | –10,108 |
| Degrees of freedom | 11 | 19 | 27 | 35 |
| BIC | 21,869 | 20,764 | 20,589 | 20,595 |
| Distribution of individuals among subgroups | n (%) | n (%) | n (%) | n (%) |
| Persistently active class | 3,905 (85) | 3,622 (79) | 3,344 (73) | 3,343 (73) |
| Intermediate class A | N/A | 592 (13) | 615 (13) | 629 (14) |
| Intermediate class B | N/A | N/A | 377 (8) | 276 (6) |
| Intermediate class C | N/A | N/A | N/A | 151 (3) |
| Resolving class | 702 (15) | 393 (9) | 271 (6) | 208 (5) |
| Odds of subgroup membership by patient factor | OR (95% Cl) | OR (95% Cl) | OR (95% Cl) | OR (95% Cl) |
| “Persistently active” vs “Resolving” class | ||||
| Female | 1.63 (1.35–1.95) | 1.73 (1.36 2.19) | 1.68 (1.24–2.27) | 1.91 (1.30 2.79) |
| Income <$50,000/y | 1.69 (1.37–2.08) | 1.68 (1.28 2.21) | 1.74 (1.23–2.45) | 1.55 (1.03–2.34) |
| History of atopy | 1.36 (1.10–1.67) | 1.55 (1.19 2.02) | 1.76 (1.27–2.46) | 2.07 ( 1.40–3.07) |
| Nonwhite race | 2.38 (1.94–2.91) | 2.94 (2.25 3.84) | 3.57 (2.54–5.01) | 4.24 (2.80–6.42) |
| Age of onset (y) | 0.91 (0.88 0.93) | 0.88 (0.85 0.91) | 0.79 (0.75–0.85) | 0.81 (0.75–0.88) |
| “Intermediate class A” vs “Resolving” class | ||||
| Female | 1.19 (0.88 1.62) | 1.47 (1.04–2.07) | 1.63 (1.08 2.46) | |
| Income <$50,000/y | 0.78 (0.55 1.10) | 0.97 (0.66–1.42) | 0.90 (0.57 1.43) | |
| History of atopy | 1.19 (0.85–1.66) | 1.28 (0.88–1.85) | 1.45 (0.93 2.24) | |
| Nonwhite race | 1.62 (1.14–2.28) | 1.67 (1.14–2.45) | 1.99 (1.26 3.14) | |
| Age of onset (y) | 0.97 (0.93 1.01) | 0.96 (0.91 1.01) | 0.98 (0.92 1.04) | |
| “Intermediate class B” vs “Resolving” class | ||||
| Female | 0.92 (0.61–1.39) | 1.24 (0.70–2.20) | ||
| Income <$50,000/y | 0.77 (0.48–1.22) | 0.84 (0.45 1.55) | ||
| History of atopy | 1.20 (0.77–1.89) | 1.21 (0.68 2.15) | ||
| Nonwhite race | 1.71 (1.08–2.71) | 2.18 (1.18–4.04) | ||
| Age of onset (y) | 0.97 (0.92–1.03) | 1.04 (0.97–1.11) | ||
| “Intermediate class C” vs “Resolving” class | ||||
| Female | 1.03 (0.57 1.85) | |||
| Income <$50,000/y | 0.45 (0.23–0.89) | |||
| History of atopy | 2.42 (1.18–4.98) | |||
| Nonwhite race | 1.73 (0.87 3.44) | |||
| Age of onset (y) | 1.00 (0.92–1.09) | |||
BIC, Bayesian information criterion; N/A, not applicable.