Table 2.
NNT to prevent one major vascular event in each sample profile
| Absolute 5 year risk of fatal and non-fatal CVD eventsa, % | RR reduction in major vascular events from taking statinsb (95% CI) | Absolute risk reduction of major vascular events from taking statins, % | NNT, n |
|---|---|---|---|
| Low risk (<1) | 0.75 (0.70 to 0.80) | 0.25 | ≥400 |
| Moderate risk (1–7.4) | 0.75 (0.70 to 0.80) | 0.25–1.9 | 400–53 |
| High risk (7.5–15.9) | 0.75 (0.70 to 0.80) | 1.9–4.0 | 53–25 |
| Very high risk (≥16) | 0.75 (0.70 to 0.80) | 4.0 | ≤25 |
a
Risk conversions are available from the authors on request.
b
RR reported for the outcome ‘Major vascular events’ as reported in Cholesterol Treatment Trialists Collaboration.26 NNT = numbers needed to treat. RR = risk ratio.