Table 3. Subgroup analysis according to the type of technique used to detect mammaglobin in the node.
| Technique / Pooled measure |
RT-PCR | BLN assay | ||||||
|---|---|---|---|---|---|---|---|---|
| Value | CI | I2 (%) | P | Value | CI | I2 (%) | P | |
| Sensitivity | 86% | 82%-89% | 78.1 | <0.0001 | 76% | 71%-80% | 71.5 | 0.0009 |
| Specificity | 82% | 80%-84% | 86.4 | <0.0001 | 95% | 94%-96% | 37.4 | 0.1312 |
| Positive Likelihood ratio | 4.80 | 3.63–6.36 | 76.4 | <0.0001 | 16.03 | 12.25–20.98 | 21.8 | 0.2565 |
| Negative Likelihood ratio | 0.17 | 0.09–0.32 | 81.2 | <0.0001 | 0.21 | 0.15–0.31 | 63.8 | 0.0072 |
| Diagnostic OR | 33.75 | 20.29–56.13 | 25.7 | 0.1843 | 81.57 | 50.93–130.63 | 31.1 | 0.1798 |
| sROC Curve | AUC = 0.9178 Q = 0.8509 SE(Q) = 0.0166 |
AUC = 0.9717 Q = 0.9226 SE(Q) = 0.0166 |
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