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. 2019 May 23;14(5):e0217143. doi: 10.1371/journal.pone.0217143

Table 3. Bivarite and multivariable models results for the associations between environmental factors and in hospital mortality after COPD exacerbation hospital admissions for study time periods (1, 1.5, 2 and 3 weeks before hospitalization).

Unadjusted Adjusted
Environmental factor (Unit) OR (95% CI) p-value OR (95% CI) p-value
1 week
Temperature (°C) 0.98 (0.97; 0.99) <0.001 0.98 (0.97; 0.99) <0.001
Humidity (%) 0.99 (0.99; 1.01) 0.526 1.00 (0.99; 1.00) 0.096
NO2 (Bg/m3) 0.98 (0.93; 1.04) 0.567 0.98 (0.92; 1.04) 0.475
SO2 (Bg/m3) 0.99 (0.97; 1.02) 0.681 1.01 (0.98; 1.04) 0.516
O3 (Bg/m3) 0.96 (0.93; 0.99) 0.011 0.95 (0.92; 0.99) 0.015
PM10 (Bg/m3) 0.95 (0.90; 1.01) 0.112 0.94 (0.88; 1.00) 0.051
CO (Bg/m3) 1.05 (0.99; 1.12) 0.062 1.05 (0.99; 1.12) 0.099
1.5 weeks
Temperature (°C) 0.98 (0.98; 0.99) <0.001 0.98 (0.97; 0.99) <0.001
Humidity (%) 1.00 (1.00; 1.00) 0.349 1.00 (1.00; 1.00) 0.959
NO2 (Bg/m3) 0.91 (0.87; 0.96) <0.001 0.92 (0.87; 0.98) 0.007
SO2 (Bg/m3) 0.98 (0.96; 1.01) 0.183 1.00 (0.97; 1.02) 0.826
O3 (Bg/m3) 0.97 (0.94; 0.99) 0.029 0.95 (0.91; 0.98) 0.002
PM10 (Bg/m3) 0.89 (0.84; 0.94) <0.001 0.89 (0.83; 0.95) <0.001
CO (Bg/m3) 1.03 (0.98; 1.08) 0.226 1.04 (0.99; 1.09) 0.139
2 weeks
Temperature (°C) 0.99 (0.98; 0.99) 0.003 0.99 (0.98; 0.99) <0.001
Humidity (%) 1.00 (0.99; 1.01) 0.886 0.99 (0.99; 1.01) 0.473
NO2 (Bg/m3) 0.99 (0.94; 1.04) 0.626 0.99 (0.93; 1.05) 0.704
SO2 (Bg/m3) 0.99 (0.96; 1.01) 0.289 0.99 (0.96; 1.02) 0.427
O3 (Bg/m3) 0.96 (0.93; 0.99) 0.006 0.96 (0.93; 0.99) 0.018
PM10 (Bg/m3) 0.95 (0.89; 1.01) 0.065 0.94 (0.88; 1.00) 0.053
CO (Bg/m3) 1.03 (0.98; 1.08) 0.208 1.04 (0.98; 1.09) 0.198
3 weeks
Temperature (°C) 0.99 (0.98; 0.99) 0.012 0.99 (0.98; 0.99) 0.004
Humidity (%) 1.00 (0.99; 1.00) 0.767 0.99 (0.99; 1.00) 0.704
NO2 (Bg/m3) 1.03 (0.98; 1.08) 0.293 1.00 (0.94; 1.06) 0.946
SO2 (Bg/m3) 0.99 (0.97; 1.01) 0.436 0.99 (0.97; 1.02) 0.713
O3 (Bg/m3) 0.95 (0.92; 0.97) <0.001 0.94 (0.91; 0.98) 0.001
PM10 (Bg/m3) 0.97 (0.92; 1.03) 0.306 0.94 (0.88; 1.00) 0.058
CO (Bg/m3) 1.06 (1.01; 1.11) 0.011 1.06 (1.01; 1.12) 0.035

NO2, nitrogen dioxide; SO2, sulfur dioxide; O3, ozone; PM10, particulate matter up to 10 μg/ m3 in size; CO: carbon monoxide; OR, odds ratio; 95% CI, 95% of confidence interval.