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. 2019 May 23;14(5):e0217347. doi: 10.1371/journal.pone.0217347

Table 3. Multivariable weighted logistic regression models of factors associated with gastroenteritis in adults, stratified by age groups.

18–24 years
(n = 555)
25–44 years
(n = 1,784)
45–64 years
(n = 2,892)
65+ years
(n = 1,874)
N (%GE) ORa 95%CI N (%GE) ORa 95%CI N (%GE) ORa 95%CI N (%GE) ORa 95%CI
Children in household
    No children 411 (11) Ref 758 (6) 2,262 (5) Ref 1,863 (3) -
    0y 1 (0) n.c. 61 (13) 5 (0) n.c. 0
    1-2y 2 (0) n.c. 86 (7) 5 (0) n.c. 0
    3-12y 7 (68) 25.6 3.9–168 470 (6) 123 (6) 1.2 0.5–2.8 1 (0)
    13-17y 109 (12) 1.4 0.5–3.9 80 (2) 507 (3) 0.6 0.3–1.2 4 (0)
Children x daycareb
    No children 411 (11) - 758 (6) Ref 2,262 (5) - 1,863 (3) -
    No daycare, 0y 0 28 (14) 3.7 0.4–32 4 (0) 0
    Daycare, 0y 1 (0) 33 (11) 3.0 0.5–19 1 (0) 0
    No daycare, 1-2y 1 (0) 22 (4) 0.9 0.1–6.3 3 (0) 0
    Daycare, 1-2y 1 (0) 64 (8) 1.8 0.6–5.3 2 (0) 0
    No daycare, 3-12y 6 (78) 310 (4) 0.7 0.2–2.1 100 (6) 1 (0)
    Daycare, 3-12y 1 (0) 160 (10) 2.8 1.1–7.3 23 (7) 0
    13-17y 109 (12) 80 (2) 0.2 0.0–1.3 507 (3) 4 (0)
Gender x migrationd
    Dutch male 214 (11) - 700 (5) Ref 1,308 (4) - 977 (2) Ref
    Non-Dutch male 9 (11) 50 (16) 4.0 1.1–15 70 (1) 70 (1) 0.4 0.1–3.5
    Dutch female 324 (12) 981 (7) 1.1 0.6–2.3 1,587 (5) 768 (4) 2.1 1.1–4.2
    Non-Dutch female 8 (16) 53 (3) 0.3 0.0–2.2 117 (11) 59 (13) 6.4 2.5–17
Employment x education
    No employment 225 (6) Ref 229 (8) Ref 803 (6) Ref 1,580 (3) Ref
    Yes, low 44 (5) 0.5 0.1–2.8 194 (6) 0.8 0.2–2.5 615 (5) 0.9 0.5–1.7 24 (13) 4.6 1.1–20
    Yes, intermediate 198 (15) 1.7 0.6–4.8 536 (6) 0.5 0.2–1.2 755 (3) 0.5 0.3–1.0 14 (0) n.c.
    Yes, high 73 (12) 3.1 0.9–10 784 (6) 0.4 0.1–0.9 795 (3) 0.4 0.2–0.9 22 (0) 0.9 0.1–6.8
Comorbidities
    Cancer 0 - 18 (10) - 114 (1) - 137 (9) 3.0 1.4–6.5
    Food allergy 28 (24) - 68 (5) - 64 (5) - 29 (14) 3.5 1.3–9.3
    Immune disorderc 10 (11) - 26 (9) - 42 (5) - 22 (0) -
    Asthma 5 (26) - 12 (0) - 18 (9) - 0 -

aStandardized by gender, age (five-year age groups) and location of residence (urban, intermediate, rural).

bDay-care, kindergarten or guest parent attendance of at least one child in the household

cE.g. Guillain Barre Syndrome, Grave’s disease, Addison’s disease, sarcoidosis

dBorn in- or outside the Netherlands

GE: gastroenteritis, OR: odds ratio, 95% CI: 95% confidence interval, n.c.: non calculable