Table 4. AUROCs of 90-day mortality prediction models.
Patient Subgroup |
All Patients (n = 413) |
Variceal Bleeding (n = 248) |
Refractory Ascites (n = 165) |
Emergent TIPS¶ (n = 61) |
Elective TIPS (n = 187) |
Uncovered Stent (n = 156) |
Covered Stent (n = 254) |
---|---|---|---|---|---|---|---|
Prediction Scores | |||||||
MELD score | 0.779 [0.729, 0.829] |
0.844 [0.793, 0.895] |
0.673 [0.575, 0.772] |
0.817 [0.708, 0.927] |
0.836 [0.771, 0.901] |
0.732 [0.651, 0.813] |
0.795 [0.725, 0.864] |
MELD-Na score | 0.767 [0.718, 0.816] |
0.824 [0.771, 0.877] |
0.689 [0.596, 0.782] |
0.787 [0.671, 0.903] |
0.820 [0.753, 0.886] |
0.712 [0.630, 0.793] |
0.793 [0.727, 0.858] |
CLIF-C ACLF score | 0.695 [0.636, 0.754] |
0.687 [0.613, 0.762] |
0.707 [0.608, 0.807] |
0.665 [0.522, 0.807] |
0.705 [0.615, 0.796] |
0.657 [0.567, 0.748] |
0.728 [0.648, 0.808] |
Child-Pugh score§ | 0.673 [0.617, 0.730] |
0.713 [0.642, 0.783] |
0.640 [0.550, 0.730] |
0.602 [0.459, 0.746] |
0.722 [0.631, 0.814] |
0.583 [0.485, 0.680] |
0.714 [0.641, 0.787] |
Platelet-Albumin-Bilirubin score | 0.712 [0.654, 0.771] |
0.750 [0.681, 0.819] |
0.660 [0.559, 0.760] |
0.648 [0.503, 0.793] |
0.781 [0.703, 0.858] |
0.649 [0.553, 0.744] |
0.744 [0.668, 0.820] |
Emory Score§ | 0.667 [0.605, 0.731] |
0.709 [0.627, 0.791] |
0.623 [0.530, 0.717] |
0.585 [0.448, 0.722] |
0.640 [0.511, 0.757] |
0.614 [0.513, 0.714] |
0.689 [0.606, 0.772] |
Individual Variables | |||||||
Age | 0.559 [0.496, 0.622] |
0.524 [0.444, 0.605] |
0.622 [0.522, 0.721] |
0.503 [0.353, 0.654] |
0.566 [0.471, 0.661] |
0.591 [0.494, 0.688] |
0.549 [0.466, 0.633] |
Hemoglobin | 0.592 [0.531, 0.653] |
0.621 [0.593, 0.702] |
0.547 [0.454, 0.639] |
0.601 [0.453, 0.748] |
0.656 [0.558, 0.754] |
0.544 [0.448, 0.640] |
0.640 [0.562, 0.719] |
Sodium | 0.532 [0.464, 0.599] |
0.579 [0.493, 0.664] |
0.538 [0.433, 0.642] |
0.568 [0.421, 0.716] |
0.570 [0.457, 0.683] |
0.504 [0.409, 0600] |
0.549 [0.450, 0.647] |
Creatinine | 0.721 [0.663, 0.779] |
0.773 [0.705, 0.841] |
0.667 [0.560, 0.774] |
0.781 [0.660, 0.901] |
0.756 [0.666, 0.847] |
0.734 [0.650, 0.818] |
0.705 [0.620, 0.789] |
International normalized ratio | 0.674 [0.614, 0.734] |
0.731 [0.660, 0.802] |
0.590 [0.487, 0.623] |
0.681 [0.544, 0.819] |
0.711 [0.616, 0.805] |
0.574 [0.479, 0.668] |
0.746 [0.668, 0.824] |
Total bilirubin | 0.708 [0.649, 0.770] |
0.746 [0.676, 0.816] |
0.654 [0.554, 0.754] |
0.661 [0.516, 0.805] |
0.770 [0.687, 0.853] |
0.659 [0.564, 0.755] |
0.731 [0.653, 0.808] |
Area under the receiver operating characteristic values are displayed with [95% confidence intervals]
Key: AUROC (area under the receiver operating characteristic), TIPS (transjugular intrahepatic portosystemic shunt), MELD (Model for End Stage Liver Disease), CLIF-C ACLF (Chronic Liver Failure Consortium Organ Failure Acute on Chronic Liver Failure Score
§ n = 389
¶ Emergent placement was only considered among patients receiving TIPS for variceal bleeding.