Skip to main content
. Author manuscript; available in PMC: 2019 May 23.
Published in final edited form as: Adv Protein Chem Struct Biol. 2019 Feb 4;116:135–170. doi: 10.1016/bs.apcsb.2019.01.001

Figure 4. Structural organization of estrogen receptors.

Figure 4

Structural domains of estrogen receptor α (ERα) (595aa) and ERβ (530aa) are labeled A-F. Both receptors have 6 different structural and functional domains: N- terminal (NTD, A/B domains, AF-1), DNA binding domain (DBD, C domain), the hinge (D domain), the C-terminal region containing the ligand binding domain (LBD, E/F domain, AF-2).