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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Chem Biol Drug Des. 2019 Jan 30;93(5):865–873. doi: 10.1111/cbdd.13476

Figure 3: Distance between AcCoA and the lysine residue and measurements of bisubstrate inhibitor.

Figure 3:

A) Distance measurements between AcCoA and lysine residue. Using the crystal structure of HAT1 bound to AcCoA and H4-20 peptide (PDB: 2P0W) measurements were done to determine the distance between the sulfur of AcCoA and the ɛ-amino group of the lysine residue. B) Distance between sulfur and amine of lysine residue of bisubstrate inhibitor, Lys-CoA. LysCoA was obtained from PDB: 3BIY.