Table 1.
Body composition and metabolic characteristics of the study participants
Mean ± SE | Range | |
---|---|---|
Age (yr) | 45 ± 1 | 20–66 |
Body mass index (kg/m2) | 37.6 ± 1.1 | 19.3–68.6 |
Fat-free mass (FFM) (kg) | 56.1 ± 1.4 | 36.9–87.4 |
Fat mass (kg) | 49.7 ± 2.3 | 8.1–123.1 |
Fat mass (% body weight) | 45.6 ± 1.0 | 11.8–59.7 |
Glucose (mg/dL) | 96 ± 1 | 81–121 |
Insulin (mU/L) | 18.7 ± 1.3 | 2.2–50.9 |
Free fatty acids (μmol/L)* | 576 ± 19 | 320–1016 |
Triglyceride (mg/dL)* | 132 ± 8 | 31–327 |
HDL-cholesterol (mg/dL)* | 45 ± 2 | 24–97 |
LDL-cholesterol (mg/dL)* | 109 ± 4 | 59–240 |
HOMA-IR | 4.4 ± 0.3 | 0.5–12.4 |
HISI [100/(μmol/kg FFM/min x mU/L)] | 0.56 ± 0.07 | 0.13–3.07 |
Glucose Rd during insulin infusion (μmol/kg FFM/min) | 53 ± 3 | 17–131 |
Glucose Rd during insulin infusion (% increase ) | 217 ± 18 | 16–731 |
N=71
HDL, high-density lipoprotein; LDL, low-density lipoprotein; HOMA-IR, Homeostatic Model Assessment of Insulin Resistance; HISI, hepatic insulin sensitivity index; Glucose Rd, glucose rate of disappearance from plasma.