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150位患者EGFR少见及复合突变类型分布

Frequency of rare and complex EGFR mutations of 150 patients

Type of EGFR mutations	Frequency
Rare single mutations	105 (70.0%)
Exon 18 G719X (X=A/S/C)	46 (30.7%)
Exon 20 S768I	9 (6.0%)
Exon 21 L861Q	45 (30.0%)
Exon 19 insertion	4 (2.7%)
Exon 18 E709 deletion	1 (0.7%)
Rare complex mutations	45 (30.0%)
Exon 18 G719X and exon 20 S768I	29 (19.3%)
Exon 18 G719X and exon 21 L861Q	4 (2.7%)
Exon 18 G719X and exon 19 deletion	2 (1.3%)
Exon 18 G719X and exon 3 R108K	1 (0.7%)
Exon 20 S768I and exon 19 deletion	1 (0.7%)
Exon 20 S768I and exon 21 L858R	6 (4.0%)
Exon 20 S768I and exon 20 V769L	1 (0.7%)
Exon 20 S768I and exon 18 G724A	1 (0.7%)