3.

48例EGFR基因少见突变类型患者经EGFR TKIs治疗的反应

Response to EGFR TKIs treatment according to types of rare EGFR mutations in 48 patients

	All patients	18 G719X	21 L861Q	Other single mutations	Complex mutations	χ2	P
CR: complete response; PR: partial response; SD: stable disease; PD: progressive disease; ORR: objective response rate; DCR: disease control rate.
CR	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)		-
PR	17 (35.4%)	6 (54.5%)	6 (30.0%)	0 (0.0%)	5 (35.7%)
SD	25 (52.1%)	4 (36.4%)	11 (55.0%)	2 (66.7%)	8 (57.1%)
PD	6 (12.5%)	1 (9.1%)	3 (15.0%)	1 (33.3%)	1 (7.1%)
ORR	35.4%	54.5%	30.0%	0.0%	35.7%	3.200	0.34
DCR	87.5%	90.9%	85.0%	66.7%	92.9%	2.162	0.59