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. Author manuscript; available in PMC: 2019 May 24.
Published in final edited form as: Mol Imaging Biol. 2018 Oct;20(5):835–845. doi: 10.1007/s11307-018-1170-6

Table 2.

Distribution volume (VT) and SUVs

Regions VT (ml/cm3)
SUV
[18F]FP-(+)-DTBZ
[18F]FP-(−)-DTBZ
[18F]FP-(+)-DTBZ
[18F]FP-(−)-DTBZ
HC T1DM P value HC T1DM P value HC T1DM P value HC T1DM P value
Pancreas 166 ± 48 96 ± 37 0.04 24 ± 3 18 ±5 0.06 22.6 ± 3.6 9.9 ± 5.4 0.002 6.1 ± 1.1 3.9 ±1.5 0.03
Spleen 27 ±2 31 ±5 0.19 9±2 9±3 0.72 4.3 ± 0.7 3.7 ± 2.1 0.47 2.1 ±0.5 1.7 ±0.5 0.22
Renal cortex 23 ±3 21 ±4 0.22 10 ±2 10 ±2 0.98 3.5 ± 0.7 2.3 ± 1.0 0.05 2.6 ± 0.4 2.0 ± 0.6 0.07

Vt values were derived from the MA1 model, and SUVs were calculated from 60 to 120 min post injection. Values are expressed as mean±SD for healthy controls (HC, n = 6) and T1DM patients (n = 4). Group differences were tested using the t test