. Author manuscript; available in PMC: 2019 May 24.

Published in final edited form as: Mol Imaging Biol. 2018 Oct;20(5):835–845. doi: 10.1007/s11307-018-1170-6

Table 3.

Non-displaceable distribution volume (V_ND) and pancreatic BP_nd

Method	V_ND		α			Pancreatic BP_ND
Method	HC	T1DM	HC	T1DM	All subjects	HC	T1DM	P value	% difference
1. V_T(+,spleen)	27 (8)	31 (17)				5.0 (27)	2.2 (55)	0.01	56
2. V_T(+,renal cortex)	23 (l1)	21 (18)				6.2 (32)	3.8 (51)	0.10	38
3. V_T(−,pancreas)	24 (14)	18 (26)				6.3 (50)	4.3 (40)	0.29	31
4. V_T(+,spleen)/α_spleen	62 (8)^*	70 (17)^*	0.37 (25)	0.54 (40)	0.44 (38)	1.6 (36)^*	0.40 (132)^*	0.01	75
5. V_T(+,renal cortex)/α_renal	46 (11)^*	41 (18)^*	0.45 (21)	0.60 (27)	0.51 (28)	2.7 (38)^*	1.5 (68)^*	0.10	45

V_nd values and α ratios were derived from the MA1 V_T values using three methods. See text for details. Data are expressed as mean (COV%). Group differences in pancreatic BP_nd were compared using t test

α_spleen and α_renal from all subjects were used to calculate V_nd and BP_nd