Table 2.
Patient characteristics by group
| SMA1 (n = 237) | No CCC (n = 632,467) | Other CCC (n = 224,953) | SMA1 vs no CCCa | SMA1 vs other CCCa | |
|---|---|---|---|---|---|
| Female (%) | 56.9 (54.7–70.8) | 44.1 (43.9–44.2) | 43.6 (43.2–44.0) | p = 0.0085 | p = 0.0069 |
| Age category (%)b | |||||
| 0–1 years (0) | 62.7 (54.7–70.8) | 63.5 (62.8–64.2) | 59.8 (58.4–61.2) | p = 0.8539 | p = 0.4954 |
| 1 + years (1, 2) | 37.3 (29.2–45.3) | 36.5 (35.8–37.2) | 40.2 (38.8–41.6) | p = 0.8539 | p = 0.4954 |
| Insurance coverage (%)b | |||||
| Medicare | 0.0 (0.0–0.0) | 0.2 (0.1–0.3) | 0.4 (0.2–0.5) | N/Ab | N/Ab |
| Medicaid | 45.3 (36.3–54.4) | 60.4 (59.0–61.7) | 57.1 (54.7–59.4) | p = 0.0006 | p = 0.0049 |
| Private insurance | 45.9 (37.5–54.4) | 32.9 (31.6–34.2) | 34.9 (33.0–36.9) | p = 0.0009 | p = 0.0046 |
| Self-pay/uninsured/other | 8.7 (1.7–15.7) | 6.5 (5.9–7.1) | 7.7 (5.9–9.4) | p = 0.4705 | p = 0.7257 |
| No. of procedure codes billed (%) | |||||
| 0 | 18.1 (12.6–23.5) | 60.6 (59.3–62) | 29.9 (28.5–31.4) | p < 0.0001 | p = 0.0003 |
| ≥ 1 | 82.0 (76.5–87.4) | 39.4 (38.0–40.7) | 70.1 (68.6–71.5) | p < 0.0001 | p = 0.0003 |
| Hospital mortality (%) | 13.4 (7.7–19.1) | 0.12 (0.10–0.13) | 2.5 (2.4–2.7) | p < 0.0001 | p < 0.0001 |
| Ventilatory support (%) | 66.1 (58.1–74.1) | 3.3 (3.1–3.6) | 20.3 (19.6–20.9) | p < 0.0001 | p < 0.0001 |
| Nutritional support (%) | 38.3 (30–46.7) | 2.9 (2.5–3.2) | 19.3 (17.8–20.8) | p < 0.0001 | p < 0.0001 |
| Respiratory disorders (%) | 78.7 (72.9–84.5) | 19.3 (18.5–20.1) | 30.4 (29.4–31.4) | p < 0.0001 | p < 0.0001 |
| Respiratory infections (%) | 54.5 (47.1–61.9) | 38.0 (37.2–38.8) | 24.3 (23.6–25.0) | p < 0.0001 | p < 0.0001 |
| LOS (mean, days) | 15.1 (10.9–19.2) | 3.4 (3.3–3.5) | 11.8 (11.3–12.2) | p < 0.0001 | p = 0.1116 |
| Total charges (mean, $US) | 150,921 (108,944–192,899) | 19,261 (18,302–20,219) | 112,453 (104,615–120,292) | p < 0.0001 | p = 0.0654 |
| Total charges per day (mean, $US) | 11,143 (9175–13,110) | 5990 (5707–6272) | 10,359 (9679–11,039) | p < 0.0001 | p = 0.3497 |
| Total costs (mean, $US) | 50,190 (35,007–65,373) | 5862 (5514–6210) | 36,605 (34,187–39,023) | p < 0.0001 | p = 0.0724 |
Numbers within brackets are 95% confidence intervals
CCC complex chronic conditions, LOS length of stay, SMA spinal muscular atrophy
at test for means and χ2 test for proportions; p-values in bold are significant at α = 0.05
bχ2 test for proportions cannot be computed for table because SMA1 cell is zero