Table 3.
Yield of the arrhythmia and cardiomyopathy gene panel before and after 2015
| Pathogenicity class | Number of variants < 2015 | Number of variants ≥ 2015 | ||
|---|---|---|---|---|
| Arrhythmia gene panel | ||||
| Class 5 | 10 | (3.9%) | 22 | (3.2%) |
| Class 4 | 11 | (4.2%) | 28 | (4.1%) |
| Class 3 | 74 | (28.2%) | 252 | (37.2%) |
| Risk factor | 2 | (0.8%) | 2 | (0.3%) |
| No variants reported | 164 | (63.3%) | 375 | (55.4%) |
| Cardiomyopathy gene panel | ||||
| Class 5 | 86 | (11.1%) | 150 | (12.5%) |
| Class 4 | 58 | (7.5%) | 97 | (8.1%) |
| Class 3 | 179 | (23.2%) | 624 | (52.1%) |
| No variants reported | 450 | (58.2%) | 326 | (27.2%) |