Table 1.
Attribute | Levels |
---|---|
PASI 90 (percent of patients who achieve 90% skin clearance) |
90% 80% 60% 40% |
Stop rate for treatment (percentage of patients not completing treatment) |
5% 10% 30% 40% |
Bio-holiday availability (6-month break in treatment without worsening of symptoms) |
Yes No |
Risk of severe adverse events (including serious infections) |
0.2% 0.5% 2.0% 5.0% |
Injection frequency (number of injections in the first year of treatment) |
6 injections 8 injections 16 injections 26 injections |
Injection type |
IV (intravenous) SC (subcutaneous) |
Who provides injection? |
Healthcare professional at clinic Self at home |
PASI 90 90% reduction in the Psoriasis Area and Severity Index score