Table 5.
Physicians | Patients: psoriasis severity | |||||
---|---|---|---|---|---|---|
General practitioners | Non-GPs | Dermatologists only | Non-dermatologists | Mild patients only | Moderate and severe patients | |
n =36 | n =125 | n = 93 | n = 68 | n = 153 | n = 145 | |
Attribute | Coefficient ( P > z ) | Coefficient ( P > z ) | Coefficient ( P > z ) | Coefficient ( P > z ) | Coefficient ( P > z ) | Coefficient ( P > z ) |
PASI 90 (per 10% increase) | 0.2197 (0.000) | 0.1599 (0.000) | 0.1571 (0.000) | 0.1909 (0.000) | 0.1358 (0.000) | 0.1366 (0.000) |
Stop rate (per 5% increase) | − 0.0321 (0.136) | − 0.0378 (0.001) | − 0.0443 (0.001) | − 0.0269 (0.082) | − 0.0266 (0.013) | − 0.0310 (0.003) |
Bio-holiday (Yes) | 0.0087 (0.927) | 0.1968 (0.000) | 0.1719 (0.002) | 0.1355 (0.043) | 0.1630 (0.000) | 0.1915 (0.000) |
Risk AE (per 1% increase) | − 0.0579 (0.060) | − 0.1092 (0.000) | − 0.1120 (0.000) | − 0.0782 (0.000) | − 0.1328 (0.000) | − 0.0959 (0.000) |
Injection frequency (5 additional) | − 0.0003 (0.993) | − 0.0540 (0.001) | − 0.0487 (0.012) | − 0.0390 (0.092) | − 0.1130 (0.000) | − 0.1025 (0.000) |
Injection type (IV) | − 0.6554 (0.000) | − 0.4325 (0.000) | − 0.4659 (0.000) | − 0.4888 (0.000) | − 0.1243 (0.005) | − 0.0315 (0.477) |
Injection—who (HCP at clinic) | 0.4365 (0.000) | 0.0141 (0.772) | − 0.0436 (0.442) | 0.3006 (0.000) | 0.5339 (0.000) | 0.2982 (0.000) |
Observations | 1152 | 4000 | 2976 | 2176 | 4896 | 4640 |
Log likelihood | − 331.0619 | − 1240.7173 | − 921.5068 | − 654.4368 | − 1481.2026 | − 1470.9213 |
Swait − Louviere LL Ratio Test Statistic | − 27.91 | − 19.58 | − 20.74 | |||
Results | Exceeds test statistic, so samples are deemed different | Exceeds test statistic, so samples are deemed different | Exceeds test statistic, so samples are deemed different |
Bold values indicate statistical significance at the 0.05 level
AE adverse events, HCP healthcare provider, IV intravenous, PASI 90 90% reduction in the Psoriasis Area and Severity Index score