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. 2018 Oct 30;3(2):255–264. doi: 10.1007/s41669-018-0104-1

Table 5.

Subgroup analysis

Physicians Patients: psoriasis severity
General practitioners Non-GPs Dermatologists only Non-dermatologists Mild patients only Moderate and severe patients
n =36 n  =125 n  = 93 n  = 68 n  = 153 n  = 145
Attribute Coefficient ( P  >  z ) Coefficient ( P  >  z ) Coefficient ( P  >  z ) Coefficient ( P  >  z ) Coefficient ( P  >  z ) Coefficient ( P  >  z )
PASI 90 (per 10% increase) 0.2197 (0.000) 0.1599 (0.000) 0.1571 (0.000) 0.1909 (0.000) 0.1358 (0.000) 0.1366 (0.000)
Stop rate (per 5% increase) − 0.0321 (0.136) − 0.0378 (0.001) − 0.0443 (0.001) − 0.0269 (0.082) − 0.0266 (0.013) − 0.0310 (0.003)
Bio-holiday (Yes) 0.0087 (0.927) 0.1968 (0.000) 0.1719 (0.002) 0.1355 (0.043) 0.1630 (0.000) 0.1915 (0.000)
Risk AE (per 1% increase) − 0.0579 (0.060) − 0.1092 (0.000) − 0.1120 (0.000) − 0.0782 (0.000) − 0.1328 (0.000) − 0.0959 (0.000)
Injection frequency (5 additional) − 0.0003 (0.993) − 0.0540 (0.001) − 0.0487 (0.012) − 0.0390 (0.092) − 0.1130 (0.000) − 0.1025 (0.000)
Injection type (IV) − 0.6554 (0.000) − 0.4325 (0.000) − 0.4659 (0.000) − 0.4888 (0.000) − 0.1243 (0.005) − 0.0315 (0.477)
Injection—who (HCP at clinic) 0.4365 (0.000) 0.0141 (0.772) − 0.0436 (0.442) 0.3006 (0.000) 0.5339 (0.000) 0.2982 (0.000)
Observations 1152 4000 2976 2176 4896 4640
Log likelihood − 331.0619 − 1240.7173 − 921.5068 − 654.4368 − 1481.2026 − 1470.9213
Swait − Louviere LL Ratio Test Statistic − 27.91 − 19.58 − 20.74
Results Exceeds test statistic, so samples are deemed different Exceeds test statistic, so samples are deemed different Exceeds test statistic, so samples are deemed different

Bold values indicate statistical significance at the 0.05 level

AE adverse events, HCP healthcare provider, IV intravenous, PASI 90 90% reduction in the Psoriasis Area and Severity Index score