Table 2.
Echocardiographic measurements from rats subjected to subcutaneous saline (Control) or Ang II infusion for 4 weeks.
| Echo parameters | Control (n = 4) | Ang II infusion (n = 8) |
|---|---|---|
| HR (bpm) | 375.32 ± 17.73 | 383.22 ± 15.53 |
| LVESV (μl) | 169.99 ± 17.25 | 123.87 ± 5.57* |
| LVEDV (μl) | 520.72 ± 13.33 | 360.55 ± 38.05* |
| SV (μl) | 350.74 ± 18.34 | 236.68 ± 33.58* |
| CO (ml/min) | 131.34 ± 7.36 | 90.47 ± 13.47 |
| EF (%) | 67.38 ± 3.24 | 63.68 ± 3.07 |
| E/A (mm/s) | 1.26 ± 0.17 | 1.14 ± 0.05 |
| E/E' (mm/s) | −17.72 ± 1.44 | −28.08 ± 2.18* |
| IVSd (mm) | 1.42 ± 0.05 | 2.09 ± 0.15* |
| LVPWd (mm) | 1.70 ± 0.16 | 2.44 ± 0.12* |
| LV Mass (mg) | 731.39 ± 23.04 | 889.15 ± 42.77* |
*
p < 0.05. HR, heart rates; LVESV, left ventricular end-systolic volume; LVEDV, left ventricular end-diastolic volume; SV, stroke volume; CO, cardiac output; EF, ejection fraction; E/A, ratio of the early to late mitral inflow velocities; E/E′, ratio between early mitral inflow velocity and mitral annular early diastolic velocity; IVSd, Interventricular septal at the end of diastole; LVPWd, Left ventricular posterior wall at the end of diastole; LV, left ventricle.