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. 2019 Apr 17;23(6):3808–3823. doi: 10.1111/jcmm.14071

Figure 8.

Figure 8

MiR‐760 induced cell cycle arrest and apoptosis by regulating PPP1R1B in MTX‐resistant CRC cells. (A, C) The cell cycle stage was detected by flow cytometry in HT29/MTX cells to explore the effect of the miR‐760/PPP1R1B axis. *P < 0.05 and **P < 0.01 compared with the NC group, #P < 0.05 compared with the PPP1R1B group. (B, D) The cell cycle stage was determined by flow cytometry in Caco2/MTX cells to explore the effect of the miR‐760/PPP1R1B axis. *P < 0.05 compared with the NC group, #P < 0.05 compared with the PPP1R1B group. (E, G) Cell apoptosis was detected by flow cytometry in HT29/MTX cells to explore the effect of the miR‐760/PPP1R1B axis. *P < 0.05 and **P < 0.01 compared with the NC group, ##P < 0.01 compared with the PPP1R1B group. (F, H) Cell apoptosis was detected by flow cytometry in Caco2/MTX cells to explore the effect of the miR‐760/PPP1R1B axis. *P < 0.05 compared with the NC group, #P < 0.05 compared with the PPP1R1B group