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. 2019 May 17;10:303. doi: 10.3389/fendo.2019.00303

Figure 5.

Figure 5

4-PBA alleviated abnormal glucose metabolism and IR in SCH mice. (A) Oral glucose tolerance test (OGTT) was implemented to detect glucose tolerance at the 17th week of administering MMI to mice in the drinking water (n = 4–6). (B) Insulin tolerance test (ITT) was implemented to assess insulin-stimulated glucose disposal at the 18th week of administering MMI to mice in the drinking water (n = 4–6). (C) The fasting plasma glucose level was assayed at the 18th week (n = 3–4). (D) The fasting plasma insulin level was assayed at the 18th week (n = 3–4). (E) Homeostasis Model Assessment-Insulin Resistance (HOMA-IR) index was calculated. (F) Insulin sensitivity index (ISI) was calculated. The data are presented as the mean ± SD. *p < 0.05 compared with vehicle treated mice group. #p < 0.05 compared with 4-PBA treated SCH mice group.