Table 2.
Effect of rutaecarpine (Rut) on echocardiographic and haemodynamic parameters in the rats subjected to abdominal artery constriction (AAC)
| Sham | AAC | AAC + Rut (L) | AAC + Rut (H) | |
|---|---|---|---|---|
| Electrocardiographic data | ||||
| LVAWd (mm) | 1.63 ± 0.09 | 2.20 ± 0.15 # | 1.74 ± 0.07* | 1.67 ± 0.10* |
| LVAWs (mm) | 2.53 ± 0.19 | 3.53 ± 0.40 # | 2.87 ± 0.24* | 2.61 ± 0.21* |
| LVPWd (mm) | 1.67 ± 0.12 | 2.37 ± 0.25 # | 2.01 ± 0.09* | 1.87 ± 0.09* |
| LVPWs (mm) | 2.65 ± 0.13 | 3.80 ± 0.35 # | 3.03 ± 0.20* | 2.83 ± 0.14* |
| LVIDd (mm) | 7.38 ± 0.24 | 7.87 ± 0.35 | 7.43 ± 0.27 | 7.39 ± 0.31 |
| LVIDs (mm) | 4.47 ± 0.35 | 4.86 ± 0.26 | 4.63 ± 0.19 | 4.54 ± 0.32 |
| Fractional shortening (%) | 34.60 ± 3.29 | 39.30 ± 4.12 | 38.6 ± 4.93 | 37.9 ± 3.48 |
| Ejection fraction (%) | 63.46 ± 6.75 | 64.82 ± 13.11 | 66.4 ± 8.93 | 65.7 ± 7.38 |
| Haemodynamic data | ||||
| SABP (mm Hg) | 126 ± 7.6 | 184 ± 8.7 # | 138 ± 8.5* | 132 ± 7.9* |
| DABP (mm Hg) | 79 ± 5.6 | 105 ± 7.4 # | 89 ± 6.9* | 84 ± 6.5* |
| Heart rate (beats/min) | 355.0 ± 21.4 | 383.5 ± 27.2 | 353.5 ± 26.5 | 365.9 ± 29.2 |
| dp/dtmax (mm Hg/s) | 4.93 ± 0.21 | 3.47 ± 0.25 # | 4.36 ± 0.13* | 4.47 ± 0.15* |
| dp/dtmin (mm Hg/s) | ‐4.77 ± 0.31 | ‐3.30 ± 0.17 # | ‐4.33 ± 0.20* | ‐4.56 ± 0.28* |
LVAWd, left ventricular anterior wall thickness during diastole; LVAWs, left ventricular anterior wall thickness during systole; LVPWd, left ventricular posterior wall thickness during diastole; LVPWs, left ventricular posterior wall thickness during systole; LVIDd, LV internal diameter during diastole; LVIDs, LV internal diameter during systole; SABP, Systolic artery blood pressure; DABP, Diastolic artery blood pressure; dp/dtmax, the maximal rate of left ventricular pressure increase; dp/dtmin, the maximal rate of left ventricular pressure decrease.
Data are mean ± SD.
One‐way ANOVA followed by post hoc test was carried out for the statistical tests. n = 10.
P < 0.05 vs Sham group.
P < 0.05 vs AAC group.