Table 2.

Correlation of miR-137 and GREM1 with clinicopathological features of cervical cancer

Clinicopathological features	n	miR-137 expression	p	GREM1 mRNA expression	p
Age (years)
≤ 40	57	0.332 ± 0.066	0.798	1.984 ± 0.195	0.860
> 40	52	0.329 ± 0.055		1.978 ± 0.156
Stage
< II stage	57	0.347 ± 0.064	0.002	1.938 ± 0.174	0.008
≥ II stage	52	0.312 ± 0.052		2.028 ± 0.170
Lymph node metastasis
No	72	0.341 ± 0.065	0.011	1.951 ± 0.165	0.012
Yes	37	0.310 ± 0.046		2.040 ± 0.187
Vascular infiltration
No	65	0.346 ± 0.070	0.001	1.950 ± 0.199	0.025
Yes	44	0.307 ± 0.032		2.027 ± 0.128
Differentiation degree
Poorly differentiated	31	0.302 ± 0.062	< 0.001	2.084 ± 0.191	< 0.001
Moderately differentiated	43	0.326 ± 0.061		1.994 ± 0.174
Well-differentiated	35	0.361 ± 0.043		1.874 ± 0.090
Tumor size (cm)
≤ 4	60	0.349 ± 0.063	< 0.001	1.928 ± 0.163	< 0.001
> 4	49	0.308 ± 0.049		2.046 ± 0.174

Statistical data were presented as mean ± standard deviation; data between two groups were analyzed by paired t-test and comparisons among multiple groups were analyzed by one-way analysis of variance

miR-137 microRNA-137, GREM1 gremlin-1