Table 5.

List of genes identified in the chromosome sequence of at least four L. brevis beer spoiler strains. 26 genes coding for hypothetical proteins were also identified

COG category and protein function	L. brevis beer-spoiler strains
	TMW1.2108	TMW1.2111	TMW1.2112	TMW1.2113	UCCLB95	UCCLBBS124	UCCLBBS449
	Energy production and conversion
Flavodoxin	+	+	+	+	+	+	+
NADH-Flavin reductase	+	+	–	–	+	+	+
Oxidoreductase	+	+	+	+	+	+	+
NADPH:quinone reductase	+	+	–	–	+	+	+
FMN-dependent NADH-azoreductase	+	+	–	–	+	+	+
Nitrobenzoate reductase	+	+	–	–	+	+	+
	Amino acid transport and metabolism
Shikimate dehydrogenase	+	+	+	+	+	+	+
Acetyltransferase GNAT family	+	+	–	–	+	+	+
Serine O-acetyltransferase EC	+	+	–	–	+	+	+
	Carbohydrate transport and metabolism
MFS transporter	+	+	–	–	+	+	+
Alpha-glucosidase	+	+	+	+	+	+	+
lycoside hydrolase	+	+	–	–	–	+	+
Hydrolase	+	+	+	+	+	+	+
Transketolase	+	+	+	+	–	–	–
MFS transporter	+	+	+	–	+	+	–
PTS system2C IIA component 1	+	+	–	–	+	+	+
Putative integral membrane protein 1	+	+	–	–	+	+	+
PTS2C EIIB 1	+	+	–	–	+	+	+
PTS mannitol transporter subunit IIA	+	+	–	–	+	+	+
Putative oligogalacturonide transporter	+	+	+	+	+	–	+
	Coenzyme transport and metabolism
6-pyruvoyl tetrahydropterin synthase	+	+	+	+	–	+	–
	Lipid transport and metabolism
NADH peroxidase	+	+	+	+	+	+	+
Peroxidase	+	+	–	–	+	+	+
Citrate lyase	+	+	–	–	+	+	+
	Transcription
Transcriptional regulator2C TetR family	+	+	–	–	+	+	+
Transcriptional regulator	+	+	+	+	+	+	+
Transcriptional regulator TetR family	+	+	–	–	+	+	+
Transcriptional regulator	+	+	+	+	+	+	+
Internalin-J	–	+	+	+	+	+	+
RNA polymerase sigma-24 subunit ECF subfamily	+	+	+	+	+	+	+
ECF-type sigma factor negative effector	+	+	+	+	+	+	+
Transcriptional regulator	+	+	+	+	+	+	+
Transcriptional regulator MarR family	+	+	–	–	+	+	+
Transcriptional regulator	+	+	–	–	+	+	+
Transcriptional regulator MarR family	+	+	–	–	+	+	+
Transcriptional regulator TetR	+	+	–	–	–	+	+
Transcriptional regulator ArsR family	+	+	–	–	+	+	+
	Cell wall/membrane/envelope biogenesis
Membrane protein	+	+	–	+	–	+	–
Cell surface protein	+	+	+	+	–	–	–
Cell surface protein	+	+	–	–	–	+	+
Endo polygalacturonase	+	+	+	+	–	–	+
Glutamyl endopeptidase precursor	+	+	+	+	+	+	+
NLP-P60 protein	+	+	+	+	+	+	+
Short-chain dehydrogenase-oxidoreductase	+	+	–	–	+	+	+
	Inorganic ion transport and metabolism
Permease	+	+	+	+	+	+	+
Permease	+	+	+	+	+	–	+
Na + −H+ antiporter	+	+	–	–	+	+	–
	General function prediction only
NADPH-quinone reductase	+	+	+	+	+	+	+
Short-chain dehydrogenase-oxidoreductase	+	+	+	+	+	+	+
Short-chain dehydrogenase	+	+	+	+	+	+	–
Cell surface adherence protein	–	–	+	+	+	+	+
Mucus-binding protein LPXTG-motif cell wall anchor	+	+	+	+	+	–	+
	Function unknown
Cell surface hydrolase	+	+	+	+	+	+	+
Membrane protein	+	+	+	+	–	+	+
Cell surface protein	+	+	–	–	+	+	+
	Defence mechanisms
ABC transporter ATP-binding protein	+	+	+	+	+	+	+
ABC transporter permease	+	+	+	+	+	+	+
Prophage protein	+	+	+	+	–	–	+

+: gene present, −: gene absent