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. 2019 May 23;20:101. doi: 10.1186/s12931-019-1049-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Maximal expiratory flow-volume curves of two representative subjects with severe emphysema or no emphysema. Patient with severe emphysema (left panel) had %LAA_-950insp = 24 whereas the patient with no emphysema (right panel) had %LAA_-950insp = 4 at CT. Note the flatter slope in the former when flow was plotted against expired volume (black lines) but not pletysmographic thoracic volume (grey lines), indicating greater thoracic gas compression at high-to-mid lung volumes