Table 5.
ESI | FEV1% | FVC% | FEV1/FVC% | TLC% | RV% | FRC% | DLco% | ||
---|---|---|---|---|---|---|---|---|---|
VIDA | p NE/ME | <.01 | <.01 | <.01 | <.01 | .28 | <.01 | <.01 | <.01 |
p NE/SE | <.01 | <.01 | <.01 | <.01 | <.01 | <.01 | <.01 | <.01 | |
p ME/SE | <.01 | <.01 | .52 | <.01 | <.01 | <.01 | <.01 | <.01 | |
Imbio LDA | p NE/ME | <.01 | .16 | .96 | <.01 | <.01 | <.01 | <.01 | .21 |
p NE/SE | <.01 | <.01 | .56 | <.01 | <.01 | <.01 | <.01 | <.01 | |
p ME/SE | <.01 | <.01 | .54 | <.01 | .42 | .23 | .02 | <.01 | |
CALIPER | p G1/G2 | <.01 | <.01 | .52 | <.01 | <.01 | <.01 | <.01 | <.01 |
p G2/G3 | <.01 | <.01 | <.01 | <.01 | .28 | <.01 | <.01 | <.01 | |
p G1/G3 | <.01 | <.01 | <.01 | <.01 | <.01 | <.01 | <.01 | <.01 |
Groups are defined according the classification performed by VIDA and Imbio LDA (NE, ME, SE) and by CALIPER (G1, G2, G3). Differences were analyzed by Games-Howell post-hoc test and p values are displayed (significant p values are in bold). Legend: DLco % percent predicted diffusing lung capacity for carbon monoxide, FEV1% percent predicted forced expiratory volume in 1 s, FRC% percent predicted functional residual capacity, FVC% percent predicted forced vital capacity, %LAA-950insp percentage of lung attenuation area with values <−950 Hounsfield Units at inspiratory CT scan, ME (moderate emphysema, 6 ≤ %LAA-950insp < 14 if VIDA or 6 ≤ %pLDA < 14 if Imbio LDA), NE (no emphysema, %LAA-950insp < 6 if VIDA or %pLDA < 6 if Imbio LDA), RV% percent predicted residual volume, SE (severe emphysema, %LAA-950insp ≥ 14 if VIDA or %LAA-950insp ≥ 14 if Imbio LDA), TLC% percent predicted total lung capacity