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. 2019 May 23;20:101. doi: 10.1186/s12931-019-1049-3

Table 5.

Post-hoc analysis of differences between groups with various degrees of emphysema as described in Table 4

ESI FEV1% FVC% FEV1/FVC% TLC% RV% FRC% DLco%
VIDA p NE/ME <.01 <.01 <.01 <.01 .28 <.01 <.01 <.01
p NE/SE <.01 <.01 <.01 <.01 <.01 <.01 <.01 <.01
p ME/SE <.01 <.01 .52 <.01 <.01 <.01 <.01 <.01
Imbio LDA p NE/ME <.01 .16 .96 <.01 <.01 <.01 <.01 .21
p NE/SE <.01 <.01 .56 <.01 <.01 <.01 <.01 <.01
p ME/SE <.01 <.01 .54 <.01 .42 .23 .02 <.01
CALIPER p G1/G2 <.01 <.01 .52 <.01 <.01 <.01 <.01 <.01
p G2/G3 <.01 <.01 <.01 <.01 .28 <.01 <.01 <.01
p G1/G3 <.01 <.01 <.01 <.01 <.01 <.01 <.01 <.01

Groups are defined according the classification performed by VIDA and Imbio LDA (NE, ME, SE) and by CALIPER (G1, G2, G3). Differences were analyzed by Games-Howell post-hoc test and p values are displayed (significant p values are in bold). Legend: DLco % percent predicted diffusing lung capacity for carbon monoxide, FEV1% percent predicted forced expiratory volume in 1 s, FRC% percent predicted functional residual capacity, FVC% percent predicted forced vital capacity, %LAA-950insp percentage of lung attenuation area with values <−950 Hounsfield Units at inspiratory CT scan, ME (moderate emphysema, 6 ≤ %LAA-950insp < 14 if VIDA or 6 ≤ %pLDA < 14 if Imbio LDA), NE (no emphysema, %LAA-950insp < 6 if VIDA or %pLDA < 6 if Imbio LDA), RV% percent predicted residual volume, SE (severe emphysema, %LAA-950insp ≥ 14 if VIDA or %LAA-950insp ≥ 14 if Imbio LDA), TLC% percent predicted total lung capacity