Table 2.
Serum content of vitamin D and correlations with other circulating factorsa
| n (%) | r | p b | |
|---|---|---|---|
| CEA | 84 (100) | 0.071 | 0.52 |
| Calcium | 82 (97.6) | 0.202 | 0.069 |
| Albumin | 84 (100) | 0.176 | 0.11 |
| CRP | 70 (83.3) | −0.285 | 0.017c |
| ESR | 75 (89.3) | −0.315 | 0.006c |
| Leukocytes | 84 (100) | −0.163 | 0.14 |
| Neutrophils | 84 (100) | −0.207 | 0.059 |
| Lymphocytes | 82 (97.6) | 0.109 | 0.33 |
| NLR | 82 (97.6) | −0.237 | 0.032c |
| Monocytes | 81 (96.4) | 0.025 | 0.83 |
| Thrombocytes | 84 (100) | −0.043 | 0.70 |
| LDH | 84 (100) | 0.150 | 0.17 |
| Creatinine | 84 (100) | 0.180 | 0.10 |
Abbreviations: CEA carcinoembryonic antigen, CRP C-reactive protein, ESR erythrocyte sedimentation rate, LDH lactate dehydrogenase, NLR neutrophil-to-lymphocyte ratio
aAll measures of circulating factors but 25-hydroxyvitamin D were log-transformed before analysis
bEstimated by Pearson correlation test
cSignificant p-value did not persist after correction for multiple comparisons of 12 datasets on circulating markers possibly related to tumor immune responses, which excluded that on CEA