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. 2019 Mar 18;5(1):e12480. doi: 10.2196/12480

Table 4.

Summary of human papillomavirus (HPV) vaccine topics generated by the Latent Dirichlet Allocation (LDA) approach.

Topic name Topic keywords Description
General vaccine debate (Topic 0) peopl, immun, diseas, get, like, flu, one, hpv, caus, children Broadly concerned with vaccine decision making; Vaccine safety; Risks of side effects; Importance of vaccination; Personal stories
HPVa-related cancer and genital warts (Topic 1) hpv, strain, cancer, caus, wart, protect, type, infect, genit, genit-wart HPV strains related to cancer and genital warts; Strains covered by vaccine
Sharing government links (Topic 2) http, www, http-www, gov, cdc, cdc-gov, nih, www-cdc, nih-gov, nlm Vaccine concerns corroborated by links to CDCb and PubMed research articles
HPV cancer prevention (Topic 3) cancer, cervic, cervic-cancer, hpv, get, women, prevent, caus, hpv-vaccin, men Gender-related vaccine and HPV concerns; cervical cancer; other HPV related cancers; recommendations for men and women
HPV-specific vaccine debate (Topic 4) effect, gardasil, studi, report, gt, hpv, death, year, side, hpv-vaccin Adverse events linked to HPV vaccination; Side effect risk; Vaccine efficacy; Debating facts (fewer personal stories than topic 0).
HPV vaccine political debate (Topic 5) peopl, hpv, make, gt, would, like, hpv-vaccin, think, one thing Parental vaccine rights; Reach of federal power; Abortion debate; Sexual education policy; General political debate; Individual politicians; Corruption
Sharing general links on HPV (Topic 6) http, com, www, http-www, org, amp, en, hpv, comment, wikipedia HPV concerns with links to news stories; Links to other Reddit threads; Generally sharing single links rather than a list of links (Topic 2)
HPV vaccination schedule (Topic 7) get, hpv, hpv-vaccin, year, got, doctor, go, shot, age, girl Age of vaccination; Preventive screenings; Medical advice; Personal stories; Deciding whether to vaccinate
Circumcision debate (Topic 8) circumcis, men, gt, risk, women, male, hiv, infect, hpv, benefit Risks and benefits of circumcision; Likelihood of contracting STIc; Cancer prevention
Sexual behaviors including HPV (Topic 9) get, hpv, sex, test, condom, peopl, like, know, partner, std Discussions of sexual behaviors; STI prevention; Vaccination; Condom use; Relationship norms

aHPV: human papillomavirus.

bCDC: Centers for Disease Control and Prevention.

cSTI: sexually transmitted infection.