FIG. 3.

Results from multiple linear regression models examining associations between log₁₀BDE-47 (ng/g lipid) and thyroid hormone parameters (log₁₀TSH: μIU/mL; free thyroxine [T4]: ng/dL; total T4: μg/dL) measured as continuous variables reported by nine North American birth cohort studies. Herbstman et al. (32) and Stapleton et al. (33) applied a natural-log transformation to BDE-47 and TSH rather than a log₁₀-transformation. Stapleton et al. (33) additionally natural-log transformed free T4. To facilitate comparison of the present results to others, final models expressing free T4 and total T4 were reanalyzed in units of ng/dL and μg/dL, respectively. Abdelouahab et al. (29) modeled free T4 measured in cord blood on a pmol/L basis. therefore, these results were excluded from the figure to accommodate the y-axis scale. Supplementary Table S8 presents summary data for BDE-47 and thyroid hormone parameters measured by each study. Color images are available online.