Table 1.

Characteristics of systemic sclerosis (SSc) patients and healthy control (HC) donors in the Zurich cohort.

Donor	Gender	Site of biopsy	Disease subtype	Disease duration (years)	mRSS	Fibrosis at the site of biopsy	Skin biopsy expression analysis	PDGF stimulation/ functional assays
SSc 1	Female	Forearm	Diffuse	10.16	4	No	x	x
SSc 2	Male	Forearm	Diffuse	1.32	16	Yes	x	x
SSc 3	Female	Forearm	Diffuse	9.16	6	No	x
SSc 4	Male	Forearm	Diffuse	0.72	n.a.	n.a.		x
SSc 5	Male	Forearm	Limited	n.a.	0	No	x
SSc 6	Female	Forearm	Limited	6.0	0	No	x
SSc 7	Female	Forearm	Limited	n.a.	0	No	x	x
SSc 8	Female	Forearm	Limited	n.a.	6	No		x
SSc 9	Female	Forearm	Limited	n.a.	3	No		x
HC 1	Female	Abdomen					x
HC 2	Female	Breast					x
HC 3	Female	Hernia surgery					x
HC 4	Male	Forearm						x
HC 5	Male	Forearm					x
HC 6	Male	Forearm					x	x
HC 7	Male	Forearm					x	x
HC 8	Female	Breast						x
HC 9	Male	Forearm						x
HC 10	Male	Forearm						x
HC 11	Female	Forearm						x
HC 12	Female	Forearm						x
HC 13	Female	Forearm						x
HC 14	Male	Forearm						x

Skin biopsies were obtained from patients fulfilling the American College of Rheumatology (ACR)/European League against Rheumatism (EULAR) 2013 criteria. The disease subset was determined according to the criteria proposed by LeRoy et al. (28). Disease duration was measured from the onset of the first non-Raynaud symptoms attributable to SSc. n.a, not available.