Table 1.
Line | Role in autophagy |
Phenotype | Mitochondrial structure |
Red/Green ratio |
Pure red puncta |
---|---|---|---|---|---|
Atg1i | Induction | Normal | Normal | ↑ | ↓ |
Atg13i | Induction | Eclosion failed at the end of pupal stage | |||
Atg6i | Nucleation | Normal | → | ↑ | |
Atg14i | Nucleation | Eclosion failed at the end of pupal stage. | Normal | ||
Atg2i | Autophagosome formation | Weak line and short lifespan | Abnormal | ↓ | ↓ |
Atg9i | Autophagosome formation | Normal | Abnormal | → | ↓ |
Atg18i | Autophagosome formation | Short lifespan | Abnormal | → | ↓ |
Atg4i | Autophagosome formation | Impaired negative geotaxis at 25 days | Normal | ↑ | ↓ |
Atg7i | Autophagosome formation | Normal | Normal | → | ↓ |