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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: J Mol Cell Cardiol. 2018 Dec 17;127:116–124. doi: 10.1016/j.yjmcc.2018.12.006

Table 1.

Summary results of the selective screening for RNAi-mediated knockdown of Atgs

Line Role in
autophagy
Phenotype Mitochondrial
structure
Red/Green
ratio
Pure red
puncta

Atg1i Induction Normal Normal
Atg13i Induction Eclosion failed at the end of pupal stage
Atg6i Nucleation Normal
Atg14i Nucleation Eclosion failed at the end of pupal stage. Normal
Atg2i Autophagosome formation Weak line and short lifespan Abnormal
Atg9i Autophagosome formation Normal Abnormal
Atg18i Autophagosome formation Short lifespan Abnormal
Atg4i Autophagosome formation Impaired negative geotaxis at 25 days Normal
Atg7i Autophagosome formation Normal Normal