Table 4.
Results of meta-regression analysis.
| Year of publication | Number of study arms | Duration of the study | PANSS Score | |||||
|---|---|---|---|---|---|---|---|---|
| P | R | P | r | P | r | P | r | |
| Withdrawal for AEs | 0.542 | 0.083 | 0.029 | 0.292 | 0.169 | 0.190 | 0.091 | 0.264 |
| All AEs | 0.308 | −0.149 | 0.125 | 0.222 | 0.290 | −0.158 | 0.052 | 0.318 |
| Nervous system disorders | 0.056 | −0.255 | 0.499 | 0.091 | 0.521 | −0.088 | 0.020 | 0.359 |
| Psychiatric disorders | 0.189 | −0.177 | 0.005 | −0.369 | 0.002 | 0.416 | 0.017 | −0.367 |
| Gastrointestinal disorders | 0.961 | −0.007 | 0.158 | 0.205 | 0.884 | 0.021 | 0.004 | 0.460 |
The effect of 4 factors (year of publication; number of study arms; duration; and PANSS score) on reported outcome measures were analyzed. P-values and r coefficients are given.
AEs, Adverse Events; PANSS, Positive and Negative Syndrome Scale.