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. 2018 Apr 19;40(1):59–65. doi: 10.1590/1678-4685-JBN-3776

Table 2. Performance of BKV viral load for the prediction of BKV-associated nephropathy, using a commercial and an in-house QPCR test.

  Sensitivity % (95% CI) Specificity % (95% CI) PPV % (CI 95%) NPV % (CI 95%)
Plasma viral load (copies/ml)        
≥3.8 log (commercial PCR kit) 88 (47-98) 96 (90-99) 64 (31-89) 99 (94-100)
≥4.1 log (commercial PCR kit) 88 (47-98) 98 (93-100) 77 (40-97) 99 (94-100)
≥6.1 log (in-house method) 87 (81-93) 100 (94-100) 73 (39-94) 100 (91-100)

Legend: CI, confidence interval; NPV, negative predictive value; PPV, positive predictive value; qPCR, quantitative real-time polymerase chain reaction.