Table 1.
Descriptive statistics of amyotrophic lateral sclerosis patients with pathogenic C9orf72 expansion (ALS-C9Pos) and without genetic mutations (ALSwoGM).
| ALS-C9Pos (n = 84) | ALSwoGM (n = 1240) | F/χ2 | p | |
|---|---|---|---|---|
| Sex, n (%) | ||||
| Male | 47 (54%) | 681 (55%) | 0.03 | 0.854 |
| Female | 37 (46%) | 559 (45%) | ||
| Mean age at onset, years (SD) | 58.49 (9.55) | 63.41 (11.6) | 14.44 | <0.001 |
| Mean age at clinical observation, years (SD) | 64.36 (9.78) | 69.82 (11.47) | 18.10 | <0.001 |
| Mean age at diagnosis, years (SD) | 59.47 (9.55) | 64.69 (11.44) | 16.69 | <0.001 |
| Diagnostic delay, months (SD) | 11.73 (8.58) | 15.35 (21.85) | 2.28 | 0.131 |
ALS-C9Pos, amyotrophic lateral sclerosis with pathogenic C9orf72 expansion; ALSwoGM, amyotrophic lateral sclerosis without genetic mutations; significant differences are signed in bold; SD, standard deviation.