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. 2019 May 17;10:1082. doi: 10.3389/fimmu.2019.01082

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Copyright © 2019 Gutierrez Jauregui, Fleige, Bubke, Rohde, Weiss and Förster.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cellular traps are found in the contact surfaces with S aureus. Microscopic evaluation at different magnification of skin samples on day 2 after implantation of osmotic pumps colonized with Staphylococcus aureus Xen29 and filled with IL-1β, H&E staining (A,B,D) anti-MPO immunostaining (C) and anti-histone H3 (citrulline R2 + R8 + R17) immunostaining (E,F). We have also detected S. aureus inside cellular traps (arrows). These are representative images for six mice under this experimental conditions.