Figure 2: Improved late reversal learning in mutant mice lacking NR1 on DAT neurons.

(A) Early reversal was defined as sessions with < 50% correct responding and late reversal as sessions with ≥50% correct responding. (B) Number of sessions to reach reversal criterion in control (white) and null mutant (blue) mice and (C) survival analysis of sessions to reversal criterion suggests similar performance between genotypes. (D) Total trials, errors, and correction trials completed during all reversal sessions were similar between genotypes. (E) Latency to respond for a correct choice, incorrect choice, and reward during all reversal sessions suggest null mutant mice were slower to make a response, but not to collect a reward. (F) Total trials during early and late reversal, (G) total errors during early and late reversal, and (H) total corrections trials during early and late reversal suggest improved performance in null mutant mice. Data expressed as mean ± SEM. *P <0.05 versus control