Skip to main content
. 2019 Jun;44(6):340-342, 344-346, 375.

Table 1.

DSM-5 Diagnostic Criteria for Major Depressive Disorder12

For a diagnosis of MDD, ≥ 5 of the following symptoms must occur nearly every day for ≥ 2 weeks:
  • Depressed mood AND/OR anhedonia; AND

  • Significant change in weight (> 5% of body weight in one month)

  • Decreased appetite

  • Insomnia or hypersomnia

  • Psychomotor agitation or retardation

  • Fatigue or loss of energy

  • Feelings of worthlessness or excessive/inappropriate guilt

  • Diminished concentration or indecisiveness

  • Recurrent thoughts of death or suicidal ideation with or without a plan

DSM-5 = Diagnostic and Statistical Manual, 5th edition; MDD = major depressive disorder