4. Lung function (FEV1, FEV1% predicted, and FVC).
| Study ID | Antibiotic class | Antibiotic | Antibiotic frequency and amount |
Mean FEV1 (SD) (trough) |
Mean FEV1 % predicted (SD) (trough) |
Mean FVC (SD) | Total number of participants (N) | Duration of treatment |
| Shafuddin 2015 | Macrolide + tetracycline | Roxithromycin + doxycycline | Continuous (300 mg + 100 mg daily) |
0.047 (026) | 1.7 (9) | 0.06 (0.46) | 88 | 12 weeks |
| Shafuddin 2015 | Macrolide | Roxithromycin | Continuous (300 mg daily) | 0.057 (0.31) | 1.87 (11) | 0.09 (0.55) | 94 | 12 weeks |
FEV1: forced expiratory volume in 1 second FVC: forced vital capacity SD: standard deviation