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In vivo antitumor efficacy against 4T1 xenograft tumors after the intravenous and oral administration of DTX solution, DTX SNEDDS and Co-loaded SNEDDS. (A) Tumor volume (n = 5). (B) Images of tumors. (C) Tumor burden (n = 5). (D) Body weight changes (n = 5). (E) H&E staining of the major organs and tumor acquired from mice bearing 4T1 tumors at the tenth day after various treatments. Scale bars represent 100 μm. (* p< .05, **p < .01).
