Table 1. Clinical characteristics of the cystic fibrosis patients included in the study.a .
| Characteristic | Total sample | Female CF patients | Male CF patients | p |
|---|---|---|---|---|
| N = 102 (100%) | n = 53 (52%) | n = 49 (48%) | ||
| Age, years | 28.1 (26.7-29.5) | 27.5 (25.7-29.3) | 28.8 (26.6-31.0) | |
| Height, cm | 166 (164-167) | 161 (160-164) | 170 (168-172) | < 0.0001 |
| Weight, kg | 48 (47-50) | 47 (45-49) | 50 (48-53) | 0.01 |
| BMI, kg/m2 | 17.5 (17.2-18.2) | 18.0 (17.2-18.9) | 17.4 (16.8-18.0) | |
| FEV1, % predicted | 25 (24-27) | 27 (24-29) | 24 (22-26) | |
| Relative time to first evaluation, years | 9.9 (8.9-10.9) | 10.4 (9.0-11.8) | 9.3 (8.0-10.7) | |
| Estimated 5-year survival, % | 30 (28-33) | 31 (27-35) | 30 (28-33) | |
| Osteoporosis, no/yes, n(%) | 49/53 (48/52) | 30/23 (57/43) | 19/30 (39/61) | |
| T-score at the lumbar spine | −2.3 (−2.1 to −2.6) | −1.99 (−1.72 to −2.26) | −2.70 (−2.34 to −3.05) | 0.004 |
| BMD at the lumbar spine Normal (T-scores > −1), n (%) | 11 (11) | 11 (21) | 8 (16) | |
| Osteopenia (T-scores ranging from −1 to −2.4), n (%) | 41 (42) | 30 (59) | 25 (49) | |
| Osteoporosis (T-scores of ≤ −2.5), n (%) | 45 (47) | 10 (20) | 18 (35) | |
| T-score at the femoral neck | −1.9 (−1.7 to −2.1) | −1.67 (−1.45 to −1.89) | −2.19 (−1.9 to −2.48) | 0.007 |
| BMD at the femoral neck Normal (T-scores > −1), n (%) | 16 (16) | 8 (16) | 3 (7) | |
| Osteopenia (T-scores ranging from −1 to −2.4), n (%) | 54 (55) | 25 (49) | 16 (35) | |
| Osteoporosis (T-scores of ≤ −2.5), n (%) | 28 (29) | 18 (35) | 27 (59) |
CF: cystic fibrosis; BMI: body mass index; and BMD: bone mineral density. aValues expressed as mean (95% CI), except where otherwise indicated.