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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Biol Psychiatry. 2018 Dec 6;85(11):946–955. doi: 10.1016/j.biopsych.2018.11.024

Table 2.

Significant gene based test results, assuming a Bonferroni threshold of .05/20,000=2.5×10 −6.

Phenotype Gene N Number Variants Beta SE p−value Method
Age of Initiation of Smoking ARHGEF37 147,010 17 .08 .017 1.9×10 −6 Burden
Smoking Initiation HEATR5A 427,262 41 −.02 .009 1.4×10 −8 SKAT
Drinks per Week ADH1C 353,265 4 −.15 .014 1.8e−27 Burden
Drinks per Week ADH1C 353,265 4 −.15 .014 1.9e−40 SKAT

Note: no significant genes were identified for the other two phenotypes.