Table 3.

Potential cut-off values of BDNF with corresponding sensitivity and specificity

	Percentile	BDNF	Sensitivity	Specificity	Youden-index
Remission	20	11.8	0.2	0.9	0.2
	30	15.2	0.4	0.9	0.2
	40	16.5	0.5	0.8	0.3
	50	17.9	0.6	0.7	0.3
	60	19.8	0.7	0.6	0.2
	70	21.1	0.8	0.4	0.2
	80	23.6	0.8	0.2	0.1
Response	20	11.8	0.2	0.9	0.1
	30	15.2	0.3	0.9	0.2
	40	16.5	0.4	0.8	0.3
	50	17.9	0.6	0.8	0.3
	60	19.8	0.6	0.6	0.2
	70	21.1	0.7	0.4	0.1
	80	23.6	0.8	0.2	0.0

Youden index = sensitivity + specificity – 1

BDNF brain-derived neurotrophic factor level in ng/ml