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. 2019 May 24;9:7803. doi: 10.1038/s41598-019-44173-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Inflammation-related biomarkers across clinical diagnoses. *p < 0,05, **p < 0.01. The group-wise comparisons were analyzed by ANCOVA adjusting by age for all biomarkers and additionally for sex in the case of sTREM2. The p-values were adjusted by Bonferroni correction for multiple comparisons (10 comparisons). Thicker horizontal bars represent the mean while whiskers represent the standard deviation. CN: cognitively normal controls, DLB: Dementia with Lewy Bodies, prodDLB: prodromal DLB, AD: Alzheimer’s disease, prodAD: prodromal AD. (a) CSF YKL-40 levels in the different clinical groups. (b) CSF sTREM2 levels in the different clinical groups. (c) CSF PGRN levels in the different clinical groups.