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. 2019 May 24;10(6):402. doi: 10.1038/s41419-019-1619-9

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Cell cycle analysis in two kifc1 knockout cell lines and b in cells treated with (100 µM) CW069 and (0.5 µM) AZ82 inhibitors of KIFC1 through PI staining and flow cytometry. The significant differences of S-phase were identified by red region. c, d The relative population of cells in S-phase and the other phases of cell cycle under various conditions. Data are represented as mean ± S.E.M. with two-tailed Student’s t-test; ns not significant; *p < 0.05; **p < 0.01; ***p < 0.001; n = 3