Table 1.
KEGG pathways with significant enriched up-regulated transcripts and proteins.
| Toxin | KEGG pathway (transcriptome) | P value | KEGG pathway (proteome) | P value |
|---|---|---|---|---|
| AFB1 | Cytokine-cytokine receptor interaction | 0.02 | Fructose and mannose metabolism | 0.00013 |
| Intestinal immune network for IgA production | 0.001739 | Retinol metabolism | 0.000283 | |
| Jak-STAT signaling pathway | 0.003656 | Chemical carcinogenesis | 0.002798 | |
| Glycosaminoglycan biosynthesis - chondroitin sulfate/dermatan sulfate | 0.003893 | Biosynthesis of amino acids | 0.004614 | |
| ECM-receptor interaction | 0.007142 | |||
| Phagosome | 0.007149 | |||
| Cell adhesion molecules (CAMs) | 0.008871 | |||
| OTA | Complement and coagulation cascades | 0.000614 | ||
| ZEN | Cell cycle | 2.72E-12 | Biosynthesis of amino acids | 0.001971 |
| DNA replication | 6.67E-11 | |||
| Fanconi anemia pathway | 5.08E-09 | |||
| Ribosome biogenesis in eukaryotes | 4.35E-08 | |||
| Pyrimidine metabolism | 9.56E-08 | |||
| Spliceosome | 6.70E-07 | |||
| RNA transport | 1.06E-06 | |||
| Mismatch repair | 8.52E-06 | |||
| Homologous recombination | 9.64E-06 | |||
| Nucleotide excision repair | 0.00104 | |||
| Base excision repair | 0.001211 | |||
| RNA polymerase | 0.001602 | |||
| mRNA surveillance pathway | 0.002268 | |||
| Purine metabolism | 0.005707 | |||
| p53 signaling pathway | 0.008001 |
P value is calculated by Fisher’s exact test with FDR correction.