Table 2.
KEGG pathways with significant enriched down-regulated transcripts and proteins.
| Toxin | KEGG pathway (transcriptome) | P value | KEGG pathway (proteome) | P value |
|---|---|---|---|---|
| AFB1 | Metabolic pathways | 0.000886 | ECM-receptor interaction | 8.14E-07 |
| Peroxisome | 0.004771 | Cell adhesion molecules (CAMs) | 4.79E-05 | |
| Fatty acid metabolism | 0.00858 | Focal adhesion | 8.65E-05 | |
| Cell cycle | 0.009167 | Axon guidance | 1.01E-04 | |
| Ribosome | 1.36E-04 | |||
| Ribosome biogenesis in eukaryotes | 3.28E-04 | |||
| Complement and coagulation cascades | 7.82E-04 | |||
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | 1.45E-03 | |||
| Cytokine-cytokine receptor interaction | 2.25E-03 | |||
| Small cell lung cancer | 2.89E-03 | |||
| Hippo signaling pathway | 4.02E-03 | |||
| Fatty acid biosynthesis | 4.09E-03 | |||
| Adherens junction | 8.27E-03 | |||
| Pathways in cancer | 8.63E-03 | |||
| Proteoglycans in cancer | 9.43E-03 | |||
| OTA | Ribosome | 1.41E-06 | ECM-receptor interaction | 1.04E-06 |
| Focal adhesion | 0.00217 | Focal adhesion | 4.83E-05 | |
| Amoebiasis | 8.06E-04 | |||
| Small cell lung cancer | 4.59E-03 | |||
| PI3K-Akt signaling pathway | 7.94E-03 | |||
| ZEN | Valine, leucine and isoleucine degradation | 0.003184 | Insulin signaling pathway | 0.008517 |
| PPAR signaling pathway | 0.003962 |
P value is calculated by Fisher’s exact test and cutoff set to 0.01.